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前言
Preface
Chapter 1 Fundamentals of Pharmaceutical Polymer Chemistry
1.1 The Concept of a Polymer
1.2 Addition Polymerization
1.3 Chain Branching; Graft and Block Copolymers
1.4 Polymer Structure and Properties
1.5 Technology of Polymerization
1.6 The Principal Monomers and Their Polymers
1.7 Physical Properties of Monomers
References
Chapter 2 Pharmaceutical Polymers: Principles and Structures
2.1 Introduction
2.2 Intra and Inter Polymer Molecular Interactions
2.3 Molecular Mass: Polydispersivity and Effects on Polymer Viscosity
2.4 Thermal Properties: Effect of Crystalline and Amorphous Phases
2.5 Mechanical Properties of Polymers
2.6 Pharmaceutical Polymers: Principles, Structures, and Applications of Pharmaceutical Delivery Systems
References
Chapter 3 Polymers as Drugs
3.1 Introduction
3.2 Polymers for Molecular Sequestration
3.3 Polyvalent Interactions and Anti-Infective Polymeric Drugs
3.4 Polymeric Drugs for the Treatment of Autoimmune Diseases
3.5 Polymeric Anti-Obesity Drugs
3.6 Polymer Therapy for Sickle Cell Disease
3.7 Conclusions and Outlook on Polymers as Drugs
References
Chapter 4 Pharmaceutical Applications of Natural Polymers
4.1 Introduction
4.2 Portals of Drug Administration in the Human Body
4.3 Transdermal Drug Delivery Devices
4.4 Topical Drug Delivery
4.5 Oral Drug Delivery System
4.6 Parenteral Drug Delivery Systems
4.7 Nasal Drug Delivery Systems
4.8 Hydrogel-Based Drug Delivery Systems
References
Chapter 5 Hydrophobic Polymers of Pharmaceutical Significance
5.1 Introduction
5.2 Examples of Hydrophobic Polymers and Their Drug Delivery Applications
5.3 Conclusions
References
Chapter 6 Polymers in Drug Delivery
6.1 Evolution of Drug Dosage Forms
6.2 Polymer Excipients
6.3 Polymers as Manufacture Aids and Sustained Release
References
Chapter 7 Pharmaceutical Nanotechnology: Overcoming Drug Delivery Challenges in Contemporary Medicine
7.1 Challenges in Delivery of Contemporary Therapeutics
7.2 Nanotechnology Solutions
7.3 Illustrative Examples of Nanotechnology Products
7.4 Multifunctional Nanotechnology
7.5 Regulatory Issues in Nano-pharmaceuticals
7.6 Conclusions and Future Outlook
References
Chapter 8 Thermal Analysis of Pharmaceutical Polymers
8.1 Introduction
8.2 Theoretical Background of Thermal Analysis
8.3 Physical and Chemical Phenomena Commonly Investigated Using Thermal Approaches
8.4 Applications of Thermal Analysis for the Characterisation of Pharmaceutical Raw Materials
8.5 Applications of Thermal Analysis for the Characterisation of Pharmaceutical Dosage Forms
8.6 Conclusion
References
Chapter 9 Applications of AFM in Pharmaceutical Polymers
9.1 Introduction
9.2 Use of AFM in Pharmaceutical Sciences
9.3 AFM Combined With Optical or Spectroscopic Techniques
9.4 Summary
References
Chapter 10 Rheology in Pharmaceutically Used Polymers
10.1 Introduction
10.2 Theoretical Background and Fundamental Concepts
10.3 Practical Issues of Rheological Measurements
10.4 Application of the Technique
10.5 Summary
References
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