"It began with a promising cancer drug, the brainchild of a gifted researcher, and grew into an insider trading scandal that ensnared one of America's most successful women. The story of ImClone Systems and its "miracle" cancer drug, Erbitux, is the quintessential business saga of the late 1990s. It's the story of big money and cutting-edgescience, celebrity, greed, and slipshod business practices; the story of biotech hype and hope and every kind of excess.At the center of it all stands a single, enigmatic figure named Sam Waksal. A brilliant, mercurial, and desperate-to-be-liked entrepreneur, Waksal was addicted to the trappings of wealth and fame that accrued to a darling of the stock market and the overheated atmosphere of biotech IPOs. At the height of his stardom, Waksal hobnobbed with Martha Stewart in New York and Carl Icahn in the Hamptons, hosted parties at his fabulous art-filled loft, and was a fixture in the gossip columns. He promised that Erbitux would "change oncology," and would soon be making $1 billion a year.But as Waksal partied late into the night, desperate cancer patients languished, waiting for his drug to come to market. When the FDA withheld approval of Erbitux, the charming scientist who had always stayed just one step ahead of bankruptcy panicked and desperately tried to cash in his stock before the bad news hit Wall Street.Waksal is now in jail, the first of the Enron-era white-collar criminals to be sentenced. Yet his cancer drug has proved more durable than his evanescent profits. Erbitux remains promising, the leading example of a new way to fight cancer, and patients and investors hope it will be available soon.

Slaphappy is reporter Thomas Hackett's penetrating look at the world of professional wrestling, for those who love the spectacle and for the sport's skeptics and the uninitiated. Through interviews with wrestlers, promoters, and fans, Hackett explores the full range of issues that swirl around wrestling culture -- fame, masculinity, violence, aggression, performance, and play. Among the lessons of professional wrestling is that deceit is a fundamental fact of American life. And yet, paradoxically, the one thing wrestling isn't is dishonest. Although wrestlers play pretend, wrestling itself doesn't pretend to be anything other than what it is -- fantastically absurd, a very American kind of madness. Celebrity-obsessed, pathologically narcissistic, murderously competitive, it both epitomizes and parodies the delusional egoism at the heart of the culture.More than that, wrestling provides its fans and performers a medium for thinking about "getting over" in America today. This spectacle of excess may be the apotheosis of American imbecility, but it is also defiant, hopeful, liberating, and unifying -- a throwback to the raucous pleasures of early theater. Fans aren't detached connoisseurs, looking satirically down on life, concealing their anxieties in the cold comforts of irony. They are total participants in a carnival of their own making, shouting epithets, throwing chairs, expatiating their worries in a crowd's triumphant foolishness.It is, Slaphappy concludes, all the stuff of human culture. Where does fantasy end and reality beginWhere does the performance stop and life take overWriting with affection and discernment, Hackett gets deep into the culture, discovering that the make-believe competition of wrestling is indeed "real" for millions of young men -- real in the sense that something real and important is at stake: their worth as men.

A Bird in the House is a series of eight interconnected short stories narrated by Vanessa MacLeod as she matures from a child at age ten into a young woman at age twenty. Wise for her years, Vanessa reveals much about the adult world in which she lives."e;Vanessa rebels against the dominance of age; she watches [her grandfather] imitate her aunt Edna; and her rage at times is such that she would gladly kick him. It takes great skill to keep this story within the expanding horizon of this young girl and yet make it so revealing of the adult world."e;-Atlantic"e;A Bird in the House achieves the breadth of scope which we usually associate with the novel (and thereby is as psychologically valid as a good novel), and at the same time uses the techniques of the short story form to reveal the different aspects of the young Vanessa."e; -Kent Thompson, The Fiddlehead"e;I am haunted by the women in Laurence's novels as if they really were alive-and not as women I've known, but as women I've been."e;-Joan Larkin, Ms. Magazine"e;Not since . . . To Kill a Mockingbird has there been a novel like this. It should not be missed by anyone who has a child or was a child."e;-Pittsburgh Post-GazetteOne of Canada's most accomplished writers, Margaret Laurence (1926-87) was the recipient of many awards including Canada's prestigious Governor General's Literary Award on two separate occasions, once for The Diviners.

In April 2003, the world watched in horror as part of Iraq's cultural heritage disintegrated among the rubble of Saddam Hussein's regime. Looters descended on the Iraq National Museum in Baghdad, Arabic manu*s disappeared from the National Library, and countless Iraqi government records were destroyed. For those to whom Iraq meant only terror, weapons of mass destruction, or oil, several thousand years of history between the Tigris and the Euphrates opened into view. Basic techniques and concepts of civilization, without which human society would not have attained its present level, had their origin there. A writing system, the prerequisite of modern and premodern societies, was part of the human knowledge that spread from Mesopotamia, as were bureaucratic techniques such as archiving, still basic to any modern administration, or early forms of monotheism. Such “firsts” will be highlighted in the following pages. But the uniqueness of the ancient Mesopotamian culture rests not only on countless innovations of this kind but, to an even greater degree, on the fact that we can follow its gradual development and its absorption into the cultural canon over a period of ten thousand years, almost without major gaps.

Recent battles in Washington over how to fix America's fiscal failures strengthened the widespread impression that economic issues sharply divide average citizens. Indeed, many commentators split Americans into two opposing groups: uncompromising supporters of unfettered free markets and advocates for government solutions to economic problems. But such dichotomies, Benjamin Page and Lawrence Jacobs contend, ring false. In Class Warthey present compelling evidence that most Americans favor free enterprise and practical government programs to distribute wealth more equitably.At every income level and in both major political parties, majorities embrace conservative egalitarianism-a philosophy that prizes individualism and self-reliance as well as public intervention to help Americans pursue these ideals on a level playing field. Drawing on hundreds of opinion studies spanning more than seventy years, including a new comprehensive survey, Page and Jacobs reveal that this worldview translates to broad support for policies aimed at narrowing the gap between rich and poor and creating genuine opportunity for all. They find, for example, that across economic, geographical, and ideological lines, most Americans support higher minimum wages, improved public education, wider access to universal health insurance coverage, and the use of tax dollars to fund these programs.In this surprising and heartening assessment, Page and Jacobs provide our new administration with a popular mandate to combat the economic inequity that plagues our nation.

Hannah Arendt's last philosophical work was an intended three-part project entitled The Life of the Mind. Unfortunately, Arendt lived to complete only the first two parts, Thinking and Willing. Of the third, Judging, only the title page, with epigraphs from Cato and Goethe, was found after her death. As the titles suggest, Arendt conceived of her work as roughly parallel to the three Critiques of Immanuel Kant. In fact, while she began work on The Life of the Mind, Arendt lectured on "e;Kant's Political Philosophy,"e; using the Critique of Judgment as her main text. The present volume brings Arendt's notes for these lectures together with other of her texts on the topic of judging and provides important clues to the likely direction of Arendt's thinking in this area.

On July 9, 1975, Dutch-born artist Bas Jan Ader set sail from Chatham, Massachusetts, on a thirteen-foot sailboat. He was bound for Falmouth, England, on the second leg of a three-part piece titled In Search of the Miraculous. The damaged boat was found south of the western tip of Ireland nearly a year later. Ader was never seen again.?Since his untimely death, Ader has achieved mythic status in the art world as a figure literally willing to die for his art. Considering the artist's legacy and concise oeuvre beyond the romantic and tragic associations that accompany his peculiar end, Alexander Dumbadze resituates Ader's art and life within the conceptual art world of Los Angeles in the early 1970s and offers a nuanced argument about artistic subjectivity that explains Ader's tremendous relevance to contemporary art.?Bas Jan Ader blends biography, theoretical reflection, and archival research to draw a detailed picture of the world in which Ader's work was rooted: a vibrant international art scene populated with peers such as Ger van Elk, William Leavitt, and Allen Ruppersberg. Dumbadze looks closely at Ader's engagement with questions of free will and his ultimate success in creating art untainted by mediation. The first in-depth study of this enigmatic conceptual artist, Bas Jan Ader is a thoughtful reflection on the necessity of the creative act and its inescapable relation to death.

In 1848 news of the discovery of gold in California triggered an enormous wave of emigration toward the Pacific. Lured by the promise of riches, thousands of settlers left behind the forests, rain, and fertile soil of the eastern United States in favor of the rough-hewn lands of the American West. The dramatic terrain they struggled to cross is so familiar to us now that it is hard to imagine how frightening-even godforsaken-its sheer rock faces and barren deserts seemed to our forebears.?Hard Road West brings their perspective vividly to life, weaving together the epic overland journey of the covered wagon trains and the compelling story of the landscape they encountered. Taking readers along the 2,000-mile California Trail, Keith Meldahl uses the diaries and letters of the settlers themselves-as well as the countless hours he has spent following the trail-to reveal how the geology and geography of the West directly affected our nation's westward expansion. He guides us through a corrugated landscape of sawtooth mountains, following the meager streams that served as lifelines through an arid land, all the way to California itself, where colliding tectonic plates created breathtaking scenery and planted the gold that lured travelers west in the first place.?"e;Alternates seamlessly between vivid accounts of the 19th-century journey and lucid explanations of the geological events that shaped the landscape traveled. . . . The reader comes away with both an appreciation for the arduous cross-continental wagon journey and an understanding of the events that created such a vast and difficult landscape."e;-Library Journal?"e;[Meldahl] draws on his professional knowledge to explain the geology of the West, showing how centuries of geological activity had a direct effect on the routes taken by the travelers. . . . Meldahl provides a novel account of the largest overland migration since the Crusades."e;-Science News

"e;I address you across more than three thousand years, you who live at the conjunction of the Fish and the Water-carrier,"e; speaks Daedalus, an artisan, inventor, and designer born into an utterly alien family of heroes who value acts of war above all else, a world where his fellow Greeks seem driven only to destroy-an existence he feels compelled to escape.In this fictional autobiography of the father of Icarus, "e;Apollo's creature,"e; a brilliant but flawed man, writer and sculptor Michael Ayrton harnesses the tales of the past to mold a myth for our times. We learn of Daedalus's increasingly ambitious artifacts and inventions; his fascination with Minoan culture, commerce, and religion, and his efforts to adapt to them; how he comes to design the maze of the horned Minotaur; and how, when he decides that he must flee yet again, he builds two sets of wax wings-wings that will be instruments of his descent into the underworld, a place of both purgatory and rebirth.A compelling mix of history, fable, lore, and meditations on the enigma of art, The Maze Maker will ensnare classicists, artists, and all lovers of story in its convolutions of life and legend. "e;I never understood the pattern of my life,"e; writes Daedalus, "e;so that I have blundered through it in a maze."e;

The Arabic philosophical fable Hayy Ibn Yaqzan is a classic of medieval Islamic philosophy. Ibn Tufayl (d. 1185), the Andalusian philosopher, tells of a child raised by a doe on an equatorial island who grows up to discover the truth about the world and his own place in it, unaided-but also unimpeded-by society, language, or tradition. Hayy's discoveries about God, nature, and man challenge the values of the culture in which the tale was written as well as those of every contemporary society.Goodman's commentary places Hayy Ibn Yaqzan in its historical and philosophical context. The volume features a new preface and index, and an updated bibliography."e;One of the most remarkable books of the Middle Ages."e;-Times Literary Supplement"e;An enchanting and puzzling story. . . . The book transcends all historical and cultural environments to settle upon the questions of human life that perpetually intrigue men."e;-Middle East Journal"e;Goodman has done a service to the modern English reader by providing a readable translation of a philosophically significant allegory."e;-Philosophy East and West"e;Add[s] bright new pieces to an Islamic mosaic whose general shape is already known."e;-American Historical Review

Our traditional image of Chicago-as a gritty metropolis carved into ethnically defined enclaves where the game of machine politics overshadows its ends-is such a powerful shaper of the city's identity that many of its closest observers fail to notice that a new Chicago has emerged over the past two decades. Larry Bennett here tackles some of our more commonly held ideas about the Windy City-inherited from such icons as Theodore Dreiser, Carl Sandburg, Daniel Burnham, Robert Park, Sara Paretsky, and Mike Royko-with the goal of better understanding Chicago as it is now: the third city.Bennett calls contemporary Chicago the third city to distinguish it from its two predecessors: the first city, a sprawling industrial center whose historical arc ran from the Civil War to the Great Depression; and the second city, the Rustbelt exemplar of the period from around 1950 to 1990. The third city features a dramatically revitalized urban core, a shifting population mix that includes new immigrant streams, and a growing number of middle-class professionals working in new economy sectors. It is also a city utterly transformed by the top-to-bottom reconstruction of public housing developments and the ambitious provision of public works like Millennium Park. It is, according to Bennett, a work in progress spearheaded by Richard M. Daley, a self-consciously innovative mayor whose strategy of neighborhood revitalization and urban renewal is a prototype of city governance for the twenty-first century. The Third City ultimately contends that to understand Chicago under Daley's charge is to understand what metropolitan life across North America may well look like in the coming decades.

Seeds have a mirrored life, the original in nature and another reflected in literature and the imagination. The Welsh proverb simultaneously expresses both the biological potential of seeds and their metaphorical power. The American philosopher and early conservationist Henry David Thoreau, who was fascinated by seeds and inspired by them, wrote, “I have great faith in a seed. Convince me that you have a seed there, and I am prepared to expect wonders.” Who cannot wonder that the largest organism on this planet, the giant redwood Sequoiadendron giganteum nicknamed “General Sherman,” which weighs roughly the equivalent of a fleet of six Boeing 747400 Jumbo Jets, germinated more than two thousand years ago from a seed weighing only a six-thousandth of a gram?

The Stone Angel, The Diviners, and A Bird in the House are three of the five books in Margaret Laurence's renowned "e;Manawaka series,"e; named for the small Canadian prairie town in which they take place. Each of these books is narrated by a strong woman growing up in the town and struggling with physical and emotional isolation.In The Stone Angel, Hagar Shipley, age ninety, tells the story of her life, and in doing so tries to come to terms with how the very qualities which sustained her have deprived her of joy. Mingling past and present, she maintains pride in the face of senility, while recalling the life she led as a rebellious young bride, and later as a grieving mother. Laurence gives us in Hagar a woman who is funny, infuriating, and heartbreakingly poignant."e;This is a revelation, not impersonation. The effect of such skilled use of language is to lead the reader towards the self-recognition that Hagar misses."e;-Robertson Davies, New York Times"e;It is [Laurence's] admirable achievement to strike, with an equally sure touch, the peculiar note and the universal; she gives us a portrait of a remarkable character and at the same time the picture of old age itself, with the pain, the weariness, the terror, the impotent angers and physical mishaps, the realization that others are waiting and wishing for an end."e;-Honor Tracy, The New Republic"e;Miss Laurence is the best fiction writer in the Dominion and one of the best in the hemisphere."e;-Atlantic"e;[Laurence] demonstrates in The Stone Angel that she has a true novelist's gift for catching a character in mid-passion and life at full flood. . . . As [Hagar Shipley] daydreams and chatters and lurches through the novel, she traces one of the most convincing-and the most touching-portraits of an unregenerate sinner declining into senility since Sara Monday went to her reward in Joyce Cary's The Horse's Mouth."e;-Time"e;Laurence's triumph is in her evocation of Hagar at ninety. . . . We sympathize with her in her resistance to being moved to a nursing home, in her preposterous flight, in her impatience in the hospital. Battered, depleted, suffering, she rages with her last breath against the dying of the light. The Stone Angel is a fine novel, admirably written and sustained by unfailing insight."e;-Granville Hicks, Saturday Review"e;The Stone Angel is a good book because Mrs. Laurence avoids sentimentality and condescension; Hagar Shipley is still passionately involved in the puzzle of her own nature. . . . Laurence's imaginative tact is strikingly at work, for surely this is what it feels like to be old."e;-Paul Pickrel, Harper's

Eduardo Lalo is one of the most vital and unique voices of Latin American literature, but his work is relatively little known in the English-speaking world. That changes now: this masterful translation of his most celebrated novel, Simone-which won the 2013 Romulo Gallegos International Novel Prize-will introduce an English-language audience to this extraordinary literary talent.A tale of alienation, love, suspense, imagination, and literature set on the streets of San Juan, Puerto Rico, Simone tells the story of a self-educated Chinese immigrant student courting (and stalking) a disillusioned, unnamed writer who is struggling to make a name for himself in a place that is not exactly a hotbed of literary fame. By turns solipsistic and political, romantic and dark, Simone begins with the writer's frustrated, satiric observations on his native city and the banal life of the university where he teaches-forces utterly at odds with the sensuality of his writing. But, as mysterious messages and literary clues begin to appear-scrawled on sidewalks and walls, inside volumes set out in bookstores, left on his answering machine and under his windshield wiper-Simone progresses into a cat-and-mouse game between the writer and his mystery stalker. When the eponymous Simone's identity is at last revealed, the writer finds in the life of this Chinese immigrant a plight not unlike his own. Traumatized and lonely, the pair moves towards bittersweet collaborations in passion, grief, and art.

Stanley Cavell is a titan of the academic world; his work in aesthetics and philosophy has shaped both fields in the United States over the past forty years. In this brief yet enlightening collection of lectures, Cavell investigates the work of two of his most tried-and-true subjects: Emerson and Wittgenstein. Beginning with an introductory essay that places his own work in a philosophical and historical context, Cavell guides his reader through his thought process when composing and editing his lectures while making larger claims about the influence of institutions on philosophers, and the idea of progress within the discipline of philosophy. In "e;Declining Decline,"e; Cavell explains how language modifies human existence, looking specifically at the culture of Wittgenstein's writings. He draws on Emerson, Thoreau, and many others to make his case that Wittgenstein can indeed be viewed as a "e;philosopher of culture."e; In his final lecture, "e;Finding as Founding,"e; Cavell writes in response to Emerson's "e;Experience,"e; and explores the tension between the philosopher and language-that he or she must embrace language as his or her?"e;form of life,"e; while at the same time surpassing its restrictions. He compares finding new ideas to discovering a previously unknown land in an essay that unabashedly celebrates the power and joy of philosophical thought.?

From the author of the bestselling Silent Night comes a close look at the embattled holiday season of 1864, when Major General W. T. Sherman gave President Lincoln the city of Savannah and paved the way for the end of the Civil War. General Sherman's Christmas opens on Thanksgiving Day 1864. Sherman was relentlessly pushing his troops nearly three hundred miles across Georgia in his "March to the Sea," to reach Savannah just days before Christmas. His methodical encroachment of the city from all sides eventually convinced Confederate general W. J. Hardee, who had refused a demand for surrender of his troops, to slip away in darkness across an improvised causeway and escape to South Carolina. In freezing rain and through terrifying fog, equipment-burdened soldiers crossed a hastily built pontoon bridge spanning the mile-wide Savannah River. Three days before Christmas, the mayor, Richard Arnold, surrendered the city, now populated mostly by women, children, and the slaves who had not fled. General Sherman then telegraphed to Abraham Lincoln, "I beg to present you as a Christmas gift the city of Savannah with 150 heavy guns plenty of ammunition also about 25.000 bales of cotton."The fight for Savannah took place as its inhabitants were anxiously preparing for Christmas. Weintraub explores how Christmas was traditionally fated in the South and what remained of the holiday to celebrate during the waning last full year of the war. Illustrated with striking period prints, General Sherman's Christmas captures the voices of soldiers and civilians on both sides of the conflict, as they neared the end of a long war.

When someone says "slow cooker," do you think of pot roast or chiliNow you can think Slow Cooked Salmon, Caramelized Onion Soup, falling-off-the-bone Lamb You Can Eat with a Spoon, and Flourless Pear Anise Soufflé. If these dishes whet your appetite, it's time to take that slow cooker out of the closet, plug it in, and get ready for Slow Cooker Cooking.Lora Brody knows her appliances. She inspired a whole new generation of bread bakers with her best-selling bread machine books. Here she pushes the slow cooker to places no one ever expected it to go, inventing fruit bases for soufflés and ice creams, reducing milk and sugar to make Dulce de Leche, and infusing oils with herbs. In addition to creating innovative takes on one-pot meals such as classic New England Boiled Dinner, Venison Stew with Mushrooms, and Osso Buco with Gremolata, here you will find recipes for ingredients that are the basis for other dishes, such as Duxelles, Braised Chestnuts, and vegetable and chicken stocks. Vegetarians will enjoy recipes such as Rago?t of Leeks, Fennel, and Celery and Virtuous Lentil Soup, and dessert lovers will rejoice when they see recipes for Hazelnut Chocolate Fondue and Coconut Rice Pudding.Creative cooking in the slow cooker doesn't mean giving up any of the convenience associated with this popular appliance. You still add the ingredients to the pot and go about your day (or evening), letting the slow cooker do all the work.Thanks to the pot's sealed insert and consistently even heat, food cooks under ideal conditions to make it tender and bring out maximum flavor. Come home to a kitchen perfumed with an aroma that promises good things to eat and find a perfectly cooked dish to enjoy.

Celebrated trainer and the Today show fitness expert Kathy Kaehler is one of Hollywood's most sought-after fitness trainers. What Kathy has done for Julia Roberts, Michelle Pfeiffer, Drew Barrymore, Cindy Crawford, Alfre Woodard, Samuel L. Jackson, Penelope Ann Miller, and Claire Forlani, among many others, she will do for you. Teenage Fitness is your ultimate fitness source. Her mission is to keep you fit for life. Reflecting on her own body image and eating problems as a teenager, Kathy will show you how to have a healthy respect for your body.She offers essential fitness techniques necessary to look and feel your absolute best. You will learn:To appreciate your own beauty To change your mind-setTo know and accept your body typeNineteen terrific eating tips to get you through your day What kind of eater you areThe 90/10 principle of pigging out Creative Fitness Suburban Fitness Urban FitnessFive-minute and twenty-minute workoutsWith Kathy's straightforward and practical fitness principles, you'll feel terrific about your body, your looks, and your life.

The brain can heal the body: that's the remarkable truth behind the body's placebo response. As one of the nation's foremost authorities on the mysterious connection between mind and body, Dr. Howard Brody introduces a radical new understanding of this phenomenon -- and how it can be used to foster good health. The body, says Brody, has an "inner pharmacy" that the brain taps into, according to what we anticipate, how we are conditioned by experience, and how we interpret events. Consider the following:In one study, people with allergies showed no response when exposed to the irritant, when they were first convinced it was something. Sham surgery has sometimes produced lasting results, indistinguishable from the results of real operations.Patients recover faster from surgery when they have window views of trees or grass, rather than brick walls.But the placebo response is more than an astonishing medical fact -- it can be put to practical use. The Placebo Response gives you access to a new kind of alternative medicine, one proven by science and found within your own body.

A beloved classic for dog lovers of all ages With a new foreword by Ann PatchettIn the 1930s, Lucy Dawson's friendly, sympathetic portraits of dogs were so popular with readers of American and British magazines that she agreed to gather them together in a book, Dogs As I See Them.The volume you now hold in your hands brings this highly collectible book back in print, replicating the original 1937 edition to a T, including all of Dawson's irresistible graphite and pastel drawings and handwritten notes printed on thick sketchbook paper. Along with Dawson's illustrations are her own amusing stories about the conduct of each of her subjects as they posed for her. Her charming reminiscences interpret the character and mood of each dog, and make us friends at once with each and every one in this gallery of endearing portraits. Dogs As I See Them is a remarkable collection dog lovers of all generations will take to their hearts.With 85 full-color and black-and-white illustrations

A full-color, plant-based guide to help you slim down and eat and feel better; filled with eighty delicious, vegan recipes and nutritious meal plans from the international phenomenon and bestselling brand BOSH!BOSH! has revolutionized plant-based eating! As the largest and fastest-growing plant-based food channel on the web, and the brand behind the smash international bestselling cookbook, BOSH! has introduced readers across the globe to fun, mouth-watering vegan recipes even meat eaters can love.Now, Henry and Ian are on a mission to help you eat well, feel better, and even lose weight. A comprehensive guide to nutritious, wholesome living using only the power of plants, BOSH!: Healthy Vegan features eighty delicious recipes and nourishing meal plans to get you started and help you stay on track.Packed full of nutrition hacks and lifestyle tips, BOSH!: Healthy Vegan will motivate anyone looking to achieve a fit, lean, and healthy body while staying vegan.