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Genomic Messages
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Ready or not, medical practice is changing. Advances in the field of genomics—the study of how our DNA is constructed and functions—have made it easier for physicians to diagnose, treat, and even predict today's many pressing health concerns. With the emergence of genomic sequencing and DNA analysis, this is an exciting moment in science, medicine, and personal health.But it's also an uncertain time, one fraught with understandable and uncomfortable questions:Can we take advantage of genomic progress and avoid genomic discriminationCan medicine be tailored to a patient's unique DNA profileHow will DNA banks and electronic medical records affect our privacy and welfareShould we screen our healthy child's DNAWhen is information too much information?In Genomic Messages, George Annas, j.d., m.p.h., and Sherman Elias, M.D., a health lawyer/bioethicist and an obstetrician-gynecologist/geneticist, respectively, answer these and other pressing questions about genomics. Together, they detail the field’s past, present, and future, while laying out its myriad legal, medical, and ethical ramifications. They empower individuals and families with the knowledge to make better decisions about their short-term and long-term health.Comprehensive, accessible, and revolutionary, Genomic Messages is the definitive guide to genomics, personalized medicine, and the future of healthcare.
The Spark Solution
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Your Days of Dieting Are NumberedAmerica's number one weight-loss website, SparkPeople.com, combines the latest science on nutrition and their experts' experience working with millions of people to lose weight to deliver everything you need to turn your body into a lean, mean, calorie-burning machine. If you've had false starts, if you've tried to diet but given up, if you've lost weight and gained it back, finally there's a lasting solution. With The Spark Solution, there will be no next time.Why waste time, energy, and money experimenting with weight-loss tactics that don't workIt's time to stop the yo-yo dieting cycle; jump-start your weight loss and get ready for long-term success—in just two weeks. With incredibly delicious, healthy recipes that enable you to eat the food you love, customizable workouts perfect for your busy life, and daily tips and inspiration that will motivate you for success, The Spark Solution is built around three key components scientifically proven to deliver results in just two weeks. The program is packed with metabolism boosters—from the frequency with which and amounts you're eating to the types of workouts you're doing. The plan is designed to make over your mind-set and tackle the most common diet bad habits. And you'll also gain the momentum needed to build healthy habits for your journey to better health and permanent weight loss.Millions have already tried it. Now you can find out their top diet secrets—not only how they lost weight but also how they discovered a path to healthy living.
The One Hundred
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"Simply put, these items make me feel classic . And there is no substitute for feeling this way. Ever." In the wildly popular The Little Black Book of Style , fashion authority Nina Garcia showed women how to think about personal style in an entirely new way. Encouraging readers to creatively assert their style identities, Nina showed women of all ages how to hone and self-edit a distinct fashion voice. With her style philosophy firmly out in the world, Nina decided to address the most popular question readers consistently ask her: Exactly what are fashion's timeless piecesThe One Hundred answers this question and provides women with a tangible style map to follow when planning a shopping trip and stocking one's closet. With illustrations from world-renowned fashion illustrator Ruben Toledo, The One Hundred contains the 100 items that Nina believes will never go out of style, and that have become absolutely indispensible for any woman reaching for her own eternal fashion look.
One Hundred Names
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Internationally bestselling author Cecelia Ahern delivers her biggest and most compelling book yet a tale of secrets, second chances, and the hidden connections that unite our lives Scandal has derailed journalist Kitty Logan's career, a setback that is soon compounded by an even more devastating loss. Constance, the woman who taught Kitty everything she knew, is dying. At her mentor's bedside, Kitty asks her, "What is the one story you always wanted to write?" The answer lies in a single sheet of paper buried in Constance's office a list of one hundred names with no notes or explanation. But before Kitty can ask her friend, it is too late. Determined to unlock the mystery and rebuild her own shaky confidence, Kitty throws herself into the investigation, tracking down each of the names on the list and uncovering their connection. Meeting these ordinary people and learning their stories, Kitty begins to piece together an unexpected portrait of Constance's life . . . and starts to understand her own.
Valdez Is Coming
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They laughed at Roberto Valdez and then ignored him. But when a dark-skinned man was holed up in a shack with a gun, they sent the part-time town constable to deal with the problem -- and made sure he had no choice but to gun the fugitive down. Trouble was, Valdez killed an innocent man. And when he asked for justice -- and some money for the dead man's woman -- they beat Valdez and tied him to a cross. They were still laughing when Valdez came back. And then they began to die...
Five Quarters of the Orange
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When Framboise Simon returns to a small village on the banks of the Loire, the locals do not recognize her as the daughter of the infamous woman they hold responsible for a tragedy during the German occupation years ago. But the past and present are inextricably entwined, particularly in a scrapbook of recipes and memories that Framboise has inherited from her mother. And soon Framboise will realize that the journal also contains the key to the tragedy that indelibly marked that summer of her ninth year. . . .
Sure of You
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A fiercely ambitious TV talk show host finds she must choose between national stardom in New York and a husband and child in San Francisco. Caught in the middle is their longtime friend, a gay man whose own future is even more uncertain. Wistful and compassionate, yet subversively funny, Sure of You could only come from Armistead Maupin.
Get Shorty
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Loan shark Chili Palmer didn't say anything when Ray Bones stole his leather jacket from Vesuvio's in Miami. He just went to Ray's house, broke his nose, took the jacket, and left. Twelve years later, on account of his boss getting whacked, Chili finds himself working for Bones and ordered to collect on a bad debt from Leo Devoe, a guy who died in a plane crash. But it turns out Leo isn't dead; he's in Las Vegas with the $300,000 the airline paid to his wife. So Chili follows him to Vegas and then on to Hollywood, where he hooks up with movie producers, actors, and studio execs. Getting Leo becomes a movie pitch unfolding in a city where every move you make is a potential scene, and making it big isn't all that different from making your bones: You gotta know who to pitch, who to hit, and how to knock 'em dead.
In a Strange City
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It is a treasured Charm City tradition. Every year on Edgar Allan Poe's birthday a figure wrapped in a dark cloak visits the renowned author's Baltimore gravesite and leaves behind three roses and half a bottle of cognac. No Baltimorean worth his or her salt would ever dream of trying to determine the true identity of the "Poe Toaster," thereby possibly destroying a cherished ritual. That's why Tess Monaghan refuses to help the odd, piglike man who wants to hire her to unmask the Visitor, who the Porcine One claims has deceived and cheated him.If nothing else, the rejected client's story has whetted Tess's curiosity—and so the following evening she and her enthusiastic boyfriend, Crow, are braving the winter chill and the graveyard dark to observe the strange, beloved rite from a respectful distance. But on this particular January 19, two caped figures approach Poe's resting place. One leaves the tribute and escapes into the night. The other dies there, felled by an assassin's bullet.Tess sees nothing that the other witnesses didn't see. She isn't working for anyone at the moment—and the homicide detective who caught this particular "red ball" is an old and dangerous nemesis—so it might be worth her while to avoid this case like the plague. But someone else wants Tess involved in the worst way. A stranger is surreptitiously leaving her roses and cognac and bizarre, cryptic clues—someone who knows Tess's habits, someone who knows who she knows and where she lives. And suddenly home is a safe haven no longer.Like it or not, Tess Monaghan is now a prime player in the murderous drama. And as the body count rises even higher, she uncovers links in a chain of greed, lies, false histories, and deadly acquisitiveness, a dangerously twisted mystery worthy of Poe himself.
The Anti-Inflammation Zone
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Combat silent inflammation -- the most serious health threat you never heard of Heart disease is the #1 killer of Americans. Cancer is the #1 fear of Americans. Dementia is the #1 concern of Americans. What do these devastating illnesses have in commonAll three have been linked to silent inflammation, a condition that occurs when the body's natural immune response goes awry. Silent inflammation can continue undetected for years, continually assaulting the heart, arteries, and even the brain -- and you will not even know it. New research confirms that obesity is a primary cause of silent inflammation. And inflammation is the smoking gun that links excess body fat to today's epidemic rise in heart disease, cancer, dementia, and countless other health threats. Although the science of this relationship is complex, the bottom line is simple: If not detected and reversed, silent inflammation will devastate generations of Americans and bankrupt an increasingly stressed health care system. The medical establishment appears to be ignorant about this problem, politicians don't talk about it -- and yet virtually everyone in the country is affected by it. In his number one New York Times bestseller The Zone, Dr. Barry Sears revolutionized the way we think about nutrition when he showed that a high-carbohydrate diet is a real risk to our health. Now, with eye-opening new research in the field of hormonal control and nutrition, Dr. Sears offers the first comprehensive plan to combat silent inflammation. This important book gives us the tools and tests we need to assess the current level of silent inflammation in our bodies -- and determine our future health. As you'll discover, the Zone dietary plan -- including supplements of high-dose, ultra-refined fish oil -- is the best way to get the hormonal control you need to reduce inflammation. In The Anti-Inflammation Zone, Dr. Sears shows exactly what steps to follow to reduce your risk of each disease and condition, or to reverse it if you have it already -- in only thirty days. And the Zone Lifestyle Program includes a week of delicious Zone-friendly meals, easy home exercises, and important stress-reducing methods -- all of which work together to put you on a path toward wellness that will improve the rest of your life. The day you start fighting silent inflammation is the day that you start to slow down the aging process -- and all the chronic diseases that come with it. Welcome to the Anti-Inflammation Zone -- and the return to wellness.
Mediterranean Women Stay Slim, Too
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Mediterranean women live lives free from empty calories, empty diet promises, impossible standards, and a "say no to food" mentality. Thanks to the influence of cooking lessons in her Italian grandmother's kitchen, Melissa Kelly, co-owner and executive chef of Primo Restaurant, has learned how every woman can extract the essence of the Mediterranean spirit and make it uniquely her own.She shares these lessons in Mediterranean Women Stay Slim, Too , along with more than one hundred diverse and mouth-watering recipes, as well as a detailed menu planner. While sampling everything from traditional Hummus to Prosciutto, Fennel, and Pear Salad with Persimmon Vinaigrette, you'll join women in enjoying the timeless, artful Mediterranean way of eating well and living a long, sensuous, beautiful life.
Good Luck Life
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Good Luck Life is the first book to explain the meanings of Chinese rituals and to offer advice on when and how to plan for Chinese holidays and special occasions such as Chinese weddings, the Red Egg and Ginger party to welcome a new baby, significant birthdays, and the inevitable funeral. Packed with practical information, Good Luck Life contains an abundance of facts, legends, foods, old-village recipes, and quick planning guides for Chinese New Year, Clear Brightness, Dragon Boat, Mid-Autumn, and many other festivals.Written with warmth and wit, Good Luck Life is beautifully designed as an easily accessible cultural guide that includes an explanation of the Lunar Calendar, tips on Chinese table etiquette for dining with confidence, and dos and don'ts from wise Auntie Lao, who recounts ancient Chinese beliefs and superstitions. This is your map for celebrating a good luck life.
A Carrion Death
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Smashed skull, snapped ribs, and a cloying smell of carrion. Leave the body for the hyenas to devour—no body, no case.But Kalahari game rangers stumble on the human corpse mid-meal. The murder wasn't perfect after all. Enter Detective David "Kubu" Bengu of the Botswana Criminal Investigation Department, an investigator whose personality and physique match his moniker, the Setswana word for hippopotamus—which is a seemingly docile beast, but one of the deadliest, and most persistent, on the continent.Beneath a mountain of lies and superstitions, Kubu uncovers a chain of crimes leading to the most powerful figures in the country—cold-bloodedly efficient and frighteningly influential enemies who can make anyone who gets in their way disappear.
Two Truths and a Lie
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Dair Canard has long been a master at weaving stories out of thin air. A natural actress, she leads a life that's a minefield of untruths she can never admit to anyone—especially not to Peyton, her husband of eight years. But the bizarre death of her best friend and fellow actor—initially thought a suicide, then believed to be murder—is forcing Dair to confront the big lie that led Peyton to fall in love with her in the first place. Haunted by the terrible events that are suddenly ripping her life wide open, Dair is struggling to find answers—taking steps that could well lead to the destruction of her marriage, her career, and even her freedom.But everyone around her has secrets and something to hide. Dair's determination to unravel the decade-old web of her own tightly woven deceptions is awakening inner demons she has fought hard to control . . . and revealing that she's closer to a killer than she ever imagined.
The Menopause Thyroid Solution
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From New York Times bestselling author and nationally recognized patient advocate Mary J. Shomon comes a groundbreaking guide to safely managing menopause through a better understanding of and better care for your thyroid.If you're one of the forty million American women struggling through menopause, you probably know all about the symptoms of fatigue, weight gain, and depression. But what you may not know is that the drop in reproductive hormones frequently triggers a thyroid slowdown—a "thyropause"—that can be the main cause for those troublesome symptoms. In fact, you may not even need hormone therapy, wild yam and progesterone creams, or herbs like black cohosh for a symptom-free menopause. What you really need is to begin to pay attention to your thyroid.In The Menopause Thyroid Solution, Mary J. Shomon will help you:Recognize the symptoms of a thyroid problem versus those of menopause Learn how to get your problems diagnosed and treated Find out what and how to eat, what medications to consider, what supplements to take, and what lifestyle changes to makeImprove your metabolism and increase your energy
26a
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A hauntingly beautiful, wickedly funny, and devastatingly moving novel of innocence and dreams that announces the arrival of a major new talent to the literary sceneIn the attic room at 26 Waifer Avenue, identical twins Georgia and Bessi Hunter share nectarines and forge their identities, while escaping from the sadness and danger that inhabit the floors below. But innocence lasts for only so long—and dreams, no matter how vivid and powerful, cannot slow the relentless incursion of the real world.
Barfly - The Movie
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The screenplay of the 1987 movie, as written by Charles Bukowski.
The Water and the Blood
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I turned and faced the road we'd come down, my face hard and set. The kids moved on without me. I could still see a slight glow and the murky, gray smoke reaching above the trees, where it spread to the south....When I thought they were out of earshot, I took a deep breath. "You lied to me," I whispered toward the building, to all the people it represented, to the hours I'd spent on those hard, split-log seats, and to my childish epiphanies born there .... "You lied," I said. "These are my best friends now."Rare is the gift of a writer who is able to conjure up the voices of very different worlds, to give them heat and power and make them sing. Such is the talent of Nancy E. Turner. Her beloved first novel, These Is My Words, opened readers to the challenges of a woman's life in the nineteenth-century Southwest. Now this extraordinary writer shifts her gaze to a very different world -- East Texas in the years of the Second World War -- and to the life of a young woman named Philadelphia Summers, known against her will as Frosty.From the novel's harrowing opening scene, Frosty's eyes survey the landscape around her -- white rural America -- with the awestruck clarity of an innocent burned by sin. In her mother and sisters she sees fear and small-mindedness; in the eyes of local boys she sees racial hatred and hunger for war. When that war finally comes, it offers her a chance for escape -to California, and the caring arms of Gordon Benally a Native-American soldier. But when she returns to Texas she must face the rejection of a town still gripped by suspicion -- and confront the memory of the crime that has marked her soul since adolescence.Propelled by the quiet power of one woman's voice, The Water and the Blood is a moving and unforgettable portrait of an America of haunted women and dangerous fools -- an America at once long perished and with us still.
Valley of Bones
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The startling reviews of Tropic of Night announced Michael Gruber as one of the most talented thriller writers to debut in many years. Now, with the much-anticipated publication of Valley of Bones, Gruber fulfills that genre-bending promise as perhaps no writer since Graham Greene, with a genuinely exhilarating thriller that simultaneously offers a profound, deeply provocative exploration of the nature of faith itself.The setting is Miami. Rookie cop Tito Morales arrives at the Trianon Hotel to investigate a routine disturbance call -- and, to his shock and horror, watches as a wealthy oilman plunges ten stories and impales himself on a nearby fence. Soon Morales is joined by detective Jimmy Paz, famous throughout the city for solving -- or at least providing a plausible solution to -- the so-called Voodoo Murders that left Miami burning months earlier.Together Paz and Morales enter the hotel and discover, in the dead man's room, a most unusual suspect, an otherworldly woman by the name of Emmylou Dideroff. She emerges from a rapturous, prayerlike state and admits that she had a motive for killing the oilman. Ultimately, she says she wants to confess, and asks for a pen and several notebooks in which to convey the details of her confession.What Emmylou writes is nothing like what Paz expects; he enlists psychologist Lorna Wise in an effort to make sense of things that go beyond Emmylou's explanation of the murder: details of childhood abuse, of other crimes committed, of regular communion with saints -- and with the devil. Is she mentally disturbed or playacting in hopes of getting declared unfit for trialOr does she really believe herself to be an instrument of GodAnd why is it that so many people -- including Paz's biological father -- are suddenly interested in the contents of these notebooks and in preventing them from becoming public?As Valley of Bones moves toward its startling and dramatic finale, Emmylou's "confessions" lead Jimmy Paz, Lorna Wise, and Tito Morales down a series of unexpected and dangerous turns that puts them in the path of perhaps the most terrifying evil imaginable and forces each of them to confront questions about faith, love, and the possibility of the miraculous.
Mr. Paradise
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Roommates Kelly and Chloe are enjoying their lives and their downtown Detroit loft just fine. Kelly is a Victoria's Secret catalog model. Chloe is an escort, until she decides to ditch her varied clientele in favor of a steady gig as girlfriend to eighty-four-year-old retired lawyer Tony Paradiso, a.k.a. Mr. Paradise.Evenings at Mr. Paradise's house, there's always an old Michigan football game on TV. And when Chloe's around, there's a cheerleader, too, complete with pleated skirt and blue-and-gold pompoms. One night Chloe convinces Kelly to join in the fun, along with Montez Taylor, Tony's smooth-talking right-hand man.But things go awry and before the end of the evening there will be two corpses, two angry hit men, one switch of identity, a safe-deposit box full of loot up for grabs, and, fast on the scene, detective Frank Delsa, who now has a double homicide -- and a beautiful, willful witness -- to add to his already heavy caseload.With a cool cast, snappy dialogue, and all the twists and turns fans crave, Mr. Paradise is Elmore Leonard at home in Detroit and sharper than ever.
In Big Trouble
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Join the world of New York Times bestselling author Laura Lippman's Tess Monaghan in the Shamus and Anthony Award-winning fourth book in the acclaimed seriesIn Big TroubleTess Monaghan has learned the hard way how to survive on the streets of Baltimore—first as a fearless investigative reporter and lately as a PI. But a new case is about to take her way out of her element.What begins with a tantalizing shard of a newspaper headline—"In Big Trouble"—above a photograph of an old boyfriend will end far away in another world, where people dress and talk differently . . . and rich people's games can have lethal consequences. Here where the sun is merciless—and curiosity can kill faster than a rattler's bite—Tess is going to have to confront her past and, hopefully, live to tell about it. For the answers she seeks about a man she thought she knew may be somehow linked to a murderer who two-steps to a very deadly drummer.
