购物车
个人中心
Cancer on Trial
￥270.76
Until the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, who were loath to assign patients randomly to competing treatments. Yet today these trials form the basis of medical oncology. How did such a spectacular change occurHow did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicineIn Cancer on Trial Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the cancer clinical trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.
Cancer Companion
￥147.15
Cancer. It's the diagnosis no one wants to hear. Unfortunately though, these days most of us have known or will know someone who receives it. But what's nextWith the diagnosis comes not only fear and uncertainty, but numerous questions, and a lot of unsolicited advice. With A Cancer Companion, esteemed oncologist Ranjana Srivastava is here to help, bringing both experience and honesty to guide cancer patients and their families through this labyrinth of questions and treatments.With candor and compassion, Srivastava provides an approachable and authoritative reference. She begins with the big questions, like what cancer actually is, and she moves on to offer very practical advice on how to find an oncologist, what to expect during and after treatments, and how to manage pain, diet, and exercise. She discusses in detail the different therapies for cancers and why some cancers are inoperable, and she skillfully addresses the emotional toll of the disease. She speaks clearly and directly to cancer patients, caretakers, and their loved ones, offering straightforward information and insight, something that many oncologists can't always convey in the office.Equipping readers with the knowledge to make informed decisions at every step of the way, A Cancer Companion is an indispensable guide by a physician who cares to educate patients as much as she does to treat them.
Children’s Party Games (Collins Gem)
￥38.36
Ever faced a crowd of fifteen 5-year olds and quaked? Well, here is your chance to bring order and calm to the party proceedings. Just consult your Gem and you can prepare for those half forgotten games such as Musical Bumps, Simon Says and Blind Man’s Buff. Collins Gem Children’s Party Games provides clear advice and instructions on the most popular family and party games. It is an invaluable guide for organizing children’s and family parties, for wet weekends, Christmas family holidays as well as train or car journeys. The clear instructions also include: Number and age of participants How long the game lasts What equipment is required How to prepare for the game For hours of family games and entertainment look no further than this Gem.
Why Us?: How Science Rediscovered the Mystery of Ourselves (Text Only)
￥73.58
The imperative to 'know thyself' is both fundamental and profoundly elusive – for how can we ever truly comprehend the drama and complexity of the human experience? In ‘Why Us?’ James Le Fanu offers a fascinating exploration of the power and limits of science to penetrate the deep mysteries of our existence, challenging the certainty that has persisted since Charles Darwin's Origin of Species that we are no more than the fortuitous consequence of a materialist evolutionary process. That challenge arises, unexpectedly, from the two major projects that promised to provide definitive proof for this most influential of scientific theories. The first is the astonishing achievement of the Human Genome Project, which, it was anticipated, would identify the genetic basis of those characteristics that distinguish humans from their primate cousins. The second is the phenomenal advance in brain imaging that now permits neuroscientists to observe the brain 'in action' and thus account for the remarkable properties of the human mind. But that is not how it has turned out. It is simply not possible to get from the monotonous sequence of genes along the Double Helix to the near infinite diversity of the living world, nor to translate the electrical firing of the brain into the creativity of the human mind. This is not a matter of not knowing all the facts. Rather, science has inadvertently discovered that its theories are insufficient to conjure the wonder of the human experience from the bare bones of our genes and brains. We stand on the brink of a tectonic shift in our understanding of ourselves that will witness the rediscovery of the central premise of Western philosophy that there is 'more than we can know'. Lucid, compelling and utterly engaging, ‘Why Us?’ offers a convincing and provocative vision of the new science of being human.
A Book of Britain: The Lore, Landscape and Heritage of a Treasured Countryside
￥368.46
In this remarkable, landmark publication, countryman Sir Johnny Scott evokes all that is romantic about the British countryside, its people, customs and traditions. Over its 600 gloriously illustrated pages, Johnny draws on his wisdom and knowledge to reveal a forgotten culture, and encourages us all to rediscover a beautiful Britain. “I always think of nightingales when spring arrives in the south of England and winter is still reluctant to release its grip north of the Border. I heard my first as a very small child while staying with my grandparents on the Ashdown Forest. My sister woke me one night with an excited whisper, 'A nightingale! You must listen to the nightingale sing!' Together we sat on the window seat, gazing across moonlit lawns towards the forest. At that moment, as if nature had not already done enough to impress, the most wonderful sound I had ever heard filled the silence, as the nightingale started to sing. A rapid succession of varied, unconstructed notes, some harsh, some liquid, sung with great exuberance and vigour, changed to a long, slow, pleading song that rose in volume to a sudden piteous crescendo, before reverting to a tune of jollity and mirth. In my mind's eye I saw it erect and glowing, somewhere in the darkness among the oak trees, but no amount of searching that morning produced a single golden feather.” Throughout the pages of A Book of Britain, Johnny Scott celebrates the landscape and people and reveals why, through centuries of careful management, conservation and cultivation, Britain looks as it does. We discover Royal forests and protected oaks; learn animal behaviour and how best to observe wildlife whether on the moors or in your garden; we learn about traditional country sports from familiar hobbies such as fishing and shooting to lesser-known activities such as “swan upping”. Johnny teaches us to look to animals and nature to predict the weather, and reveals many customs and traditions that are in danger of being lost. This book is a gift in every sense – not only in its sheer scope and presence, but in the rich legacy it will leave behind for future generations.
Short walks in the Yorkshire Dales
￥44.24
The Yorkshire Dales with its picturesque dales, ancient farmhouses and villages offer some superb country walking.This can be explored with these 20 walks, all of which are 5 miles or under in length and can easily be completed in less than 3 hours. This guide, produced in co-operation with the Ramblers and featuring Ordnance Survey mapping, is the perfect way to really appreciate the beautiful Yorkshire Dales. INCLUDES: ? 20 easy to follow walks which can be completed in 3 hours and under. ? Each walk has a detailed 1:25 000 Ordnance Survey map with the route clearly marked plus a detailed de*ion of the route. ? The walks have been chosen with issues like parking and refreshments in mind to make life easy for families. ? Packed with colour photographs of scenes you will see along the walk. The perfect guide for afternoon walks near to Sedburgh, Hawes, Settle, Ingleton, Skipton and Harrogate.
Railway Day Trips: 150 classic train journeys around Britain
￥99.08
Recommended for viewing on colour devices. An essential guide to exploring Britain by train, Railway Day Trips is ideal for anyone planning or looking for inspiration for a rail journey. From bestselling railway author Julian Holland
The Glass Universe
￥73.58
‘A biographical orrery – intricate, complex and fascinating’ The Observer ‘A peerless intellectual biography. The Glass Universe shines and twinkles as brightly as the stars themselves’ The Economist #1 New York Times bestselling author Dava Sobel returns with a captivating, little-known true story of women in science Before they even had the right to vote, a group of remarkable women were employed by Harvard College Observatory as ‘Human Computers’ to interpret the observations made via telescope by their male counterparts each night. The author of Longitude, Galileo’s Daughter and The Planets shines light on the hidden history of these extraordinary women who changed the burgeoning field of astronomy and our understanding of the stars and our place in the universe.
Selling Your Father’s Bones: The Epic Fate of the American West
￥81.52
Part historical narrative, part travelogue through the wilds of the West and part environmental polemic, 'Selling Your Father's Bones' is a thrilling journey through the history and wilderness of the stunning area of landscape that is Continental USA. In the summer of 1877, around seven hundred members of the Nez Perce Native American tribe set out on one of the most remarkable journeys in the history of the American West, a 1,700-mile exodus through the mountains, forests, badlands and prairies of modern-day Oregon, Idaho, Wyoming and Montana. They had been forced from their homes by the great wave of settlement that crashed over the West as the American nation was born. Led by their charismatic chiefs, the Nez Perce used their unerring knowledge of the landscapes they passed through to survive six battles and many more skirmishes with the pursuing United States Army, as they raced, with women, children and village elders in their care, towards the safety of the Canadian border.But all Chief Joseph, the young pastoral leader of the exodus, wanted was to return home - to his beloved Wallowa valley, which his dying father had ordered him never to abandon: 'Never sell the bones of your father and your mother. ' Now, Brian Schofield retraces the steps of that epic exodus, to tell the full dramatic story of the Nez Perce's fight for survival - and to examine the forces that drove them to take flight. The white settlement of the West had been largely motivated by patriotic fervour and religious zeal, a faith that the American continent had been laid out by God to fuel the creation of a mighty empire. But as he travels through the lands that the Nez Perce knew so well, Schofield reveals that the great project of the Western Empire has gone badly awry, as the mythology of the settlers opened the door to ecological vandalism, unthinking corporations and negligent leadership, which have lest scarred landscapes, battered communities and toxic environments.
The Music of the Primes: Why an unsolved problem in mathematics matters (Text On
￥73.58
The paperback of the critically-acclaimed popular science book by a writer who is fast becoming a celebrity mathematician. Prime numbers are the very atoms of arithmetic. They also embody one of the most tantalising enigmas in the pursuit of human knowledge. How can one predict when the next prime number will occur? Is there a formula which could generate primes? These apparently simple questions have confounded mathematicians ever since the Ancient Greeks. In 1859, the brilliant German mathematician Bernard Riemann put forward an idea which finally seemed to reveal a magical harmony at work in the numerical landscape. The promise that these eternal, unchanging numbers would finally reveal their secret thrilled mathematicians around the world. Yet Riemann, a hypochondriac and a troubled perfectionist, never publicly provided a proof for his hypothesis and his housekeeper burnt all his personal papers on his death. Whoever cracks Riemann's hypothesis will go down in history, for it has implications far beyond mathematics. In business, it is the lynchpin for security and e-commerce. In science, it has critical ramifications in Quantum Mechanics, Chaos Theory, and the future of computing. Pioneers in each of these fields are racing to crack the code and a prize of $1 million has been offered to the winner. As yet, it remains unsolved. In this breathtaking book, mathematician Marcus du Sautoy tells the story of the eccentric and brilliant men who have struggled to solve one of the biggest mysteries in science. It is a story of strange journeys, last-minute escapes from death and the unquenchable thirst for knowledge. Above all, it is a moving and awe-inspiring evocation of the mathematician's world and the beauties and mysteries it contains.
Motel Nirvana
￥63.18
A book about the New Age movement and its American heartland. It concerns the author's travels around the south-western United States of Nevada, Colorado, New Mexico and Arizona, and her encounters with some of that region's most unusual communities and individuals.
Hard, Soft and Wet
￥61.51
Who are the digital generation? They are the millions of youngsters who live with, and love, the technology with which they are growing up. This is their story. Tomorrow belongs to them. ‘This is the book which opens up the electronic frontier to those still left out in the cold, the one McLuhan would have written were he to be still surfing the Nineties’ Arena. ‘At once a romance, a cultural commentary, and a piece of travel writing which adds the virtual world to its itinerary as though it were a new place on the map. ‘ Sadie Plant, The Times Not another book about youth culture, nor cyberpunks, hackers and VR; not a computing manual; not the history of technology; but a book about the first generation of people to take the information age for granted. A personal portrait of the Wired Generation, exploring the dreams, ambitions, aesthetics and assumptions of all the kids growing up digital, worldwide. In these days of video games, PCs, multimedia and personal stereos, it’s all too easy for the sensitive kids to disappear into worlds of their own, and it happens so quickly — one birthday they’re chirpy and sociable, the next they stay home to watch Robocop for the thirty-seventh time or play Mortal Kombat yet again.
Gemstones (Collins Gem)
￥38.36
Gemstones have been a source of delight and fascination for many thousands of years. This revised edition explores the nature of gems, their beauty, rarity and durability, and the mineral properties that govern these qualities. It describes the most popular gemstones in detail and looks at how gem minerals form, where they are found and mined, and how they are identified. It includes information about the popular most popular and the lesser known stones, and describes how to distinguish the real from the fake.
The Times How to Crack Cryptic Crosswords
￥58.86
Expert crossword solver and setter, Tim Moorey, seeks to dispel the myth that cryptic crosswords are the preserve of the elite. In this easy guide, he demonstrates that anyone who enjoys words and word play can learn to solve a cryptic crossword clue. With clear pictorially presented explanations for many clues, you can revel in the deep satisfaction that comes from finishing cryptic crossword puzzles. Designed to apply to the solving of any cryptic crossword, this book develops and expands Tim’s first book, How to Master The Times Crossword, and is designed to guide the cryptic crossword beginner to an enriched solving experience. ? Contains 15 new practice puzzles from 15 different newspaper and magazine sources. ? Many new hints and tips to help every solver ? Greatly expanded lists e.g. of those all-important abbreviations you should know ? A completely new demonstration of how one solver tackles a typical daily cryptic ? Up-to-date sections on the latest help available online eg smartphone and tablet apps ? In-depth and clear explanations of every clue and puzzle answer ? Previously published as ‘How To Master The Times Crossword: The Times Cryptic Crossword Demystified’. This book is a revised and updated version.
The Quest for Mars: NASA scientists and Their Search for Life Beyond Earth (Text
￥72.99
This edition does not include illustrations. Is there life on Mars? And if not, why not? These questions have gripped mankind throughout the twentieth century. In the shadow of the new millennium, The Quest for Mars seeks the definitive answers from the dedicated NASA scientists participating in the race to discover life on the Red Planet. ‘Ever since I was a small child, I’ve believed there was life out there. When I look at the magnitude of the universe, with its billions of stars, I believe that if life developed here on Earth, it must have developed elsewhere. We simply can’t be unique. I really don’t think we’re the most intelligent life forms in the universe, but that’s just my gut feeling’, Dr Claire Parkinson, NASA scientist. Of all the planets, Mars has exerted the most powerful allure over the human intellect and imagination. Generations of astronomers have expected to find clues to the origin and destiny of Earth and its inhabitants concealed amid the red storms sweeping across the surface of Mars. Today, the mystique of Mars is even greater. Public interest in the Mars mission is sky-high; the exploits of the tiny Mars Rover ‘Sojourner’ in the summer of 1997 excited the greatest curiosity in a space mission in a generation. In The Quest for Mars Laurence Bergreen has unrestricted access to a team of NASA employees – engineers, geologists and other scientists – who are consumed by the search for proof of life on Mars. As one formidable obstacle after another attempts to scupper their quest for a deeper understanding of life on Mars and throughout the Solar System, the narrative takes us step by step through the exhilaration and the despondency of their extraordinary adventure. Nothing is off limits in this unique, behind-the-scenes story of space exploration.
BMW 3 Series - E36 Restoration Tips & Techniques
￥24.44
A practical restoration manual on the E36, the 3 Series BMWs built between 1990 & 1999. Covers all models from the 316 compact to the M3. Advice is given on acquiring a good pre-owned example plus restoring & modifying engines, bodywork, trim, electrics, suspension & mechanical parts. Detailed information on Alpina & M3 cars. A total of 148 fully illustrated colour and black & white
Leviathan
￥80.25
The story of a man’s obsession with whales, which takes him on a personal, historical and biographical journey – from his childhood to his fascination with Moby-Dick and his excursions whale-watching. All his life, Philip Hoare has been obsessed by whales, from the gigantic skeletons in London’s Natural History Museum to adult encounters with the wild animals themselves. Whales have a mythical quality – they seem to elide with dark fantasies of sea-serpents and antediluvian monsters that swim in our collective unconscious. In ‘Leviathan’, Philip Hoare seeks to locate and identify this obsession. What impelled Melville to write ‘Moby-Dick’? After his book in 1851, no one saw whales in quite the same way again. This book is an investigation into what we know little about – dark, shadowy creatures who swim below the depths, only to surface in a spray of spume. More than the story of the whale, it is also the story of our own obsessions.
Tools and Function Lists: Engineering Tools Manual
￥20.44
Tools and Function Lists: Engineering Tools Manual
Clinical Updates in the Management of Severe Asthma
￥0.01
Clinical Updates in the Management of Severe Asthma
Neuropsychopharmacology: An Introduction: A Tutorial Study Guide
￥32.62
Neuropsychopharmacology: An Introduction: A Tutorial Study Guide
Pharmacology: An Introduction: A Tutorial Study Guide
￥32.62
Pharmacology: An Introduction: A Tutorial Study Guide
